2024 Author: Jasmine Walkman | [email protected]. Last modified: 2023-12-16 08:29
Many patients with hypothyroidism struggle with their inability to lose weight, and losing weight is a challenge for them. The latest research focuses on the evaluation of two key hormones - leptin and T3.
The hormone leptin has been found to be a major regulator of body weight and metabolism. It is secreted by fat cells and leptin levels increase with fat accumulation. The increase in leptin secretion, which manifests itself with weight gain, is usually fed back to the hypothalamus as a signal that there is enough energy and stores. This stimulates the body to burn fat instead of continuing to store excess fat and stimulates the thyroid gland.
However, studies show that the majority of overweight people have difficulty losing weight due to varying degrees of leptin resistance, where leptin has a reduced ability to affect the hypothalamus and regulate metabolism. The resistance it exerts in the hypothalamus signals hunger, so many mechanisms are activated and begin to increase fat deposits as the body tries to fight the state of hunger. The mechanisms that are activated also act to increase appetite, increase insulin resistance and inhibit lipolysis (fat distribution). What is the result? Overweight and more difficult to lose weight.
When you have reduced thyroid function and it does not produce enough hormones, the effect is a slow metabolism. In addition to slowing it down, it slows down all the processes in your body from digestion to hair growth. Which in turn leads to weight gain and difficult weight loss. In this case, you should be very careful with your diet, because improper nutrition can further aggravate your situation.
In addition to all the above, people with hypothyroidism (hypothyroidism) often tend to feel tired, which makes exercise much more difficult for them because they simply have much less energy. With a slow metabolism and little energy, as you already know, losing weight turns out to be quite a difficult and unattainable goal.
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